Multitrauma-related deaths are more common in non-developed countries and approximately 50 million people in the world remain disabled after multitrauma every year. We aim of this study is to retrospectively evaluate the clinical features and risk factors affecting mortality in multitrauma patients admitted to the emergency department (ED). The study included 188 patients hospitalized from the ED to the Anesthesia Intensive Care Unit due to multitrauma. 75% of the cases were male and the mean age was 45.55 ± 19.29 years. The most common type of trauma was traffic accident 61.7% and injuries were 47.1% rib fracture. 6.9% of the cases died. When the risk factors affecting mortality were evaluated by multivariate analysis: it was determined that intubating the cases and high lactate level increased the risk of mortality independently of other variables. In these cases, the frequency of mortality and morbidity can be reduced by taking more serious precautions in the early period and by appropriate treatment management. The most effective way to reduce mortality and morbidity is to prevent trauma.