Oxidative stress in relation to chronic periodontal disease
Kluknavská Janka, Timková Silvia, Schwartzová Vladimíra, Vašková Janka
American Journal of Research in Medical Sciences. 2019;
Chronic periodontal disease is a relatively common inflammatory disease which,
untreated, can lead to premature tooth loss. Many factors, including oxidative stress,
play a role in the etiology of this disease. Various markers of oxidative stress have been
evaluated in saliva and sulcular fluid between patients with chronic periodontal disease
and healthy people in many studies, with some current studies suggesting changes in
both the local and systemic redox equilibrium of patients. Antioxidant therapy seems
to have its place in the therapeutic options for patients with gingivitis and periodontal
disease. There has been evidence of positive effects in treatment with antioxidants along
with scaling and root planning.
In the future, we anticipate that the determination of the selected antioxidant markers
could be helpful in the diagnosis of chronic periodontal disease or evaluating therapy.